RESUMO
BACKGROUND: To describe a case of bilateral multifocal chorioretinitis as the only presentation of acute West Nile virus (WNV) infection in the absence of neurological involvement. CASE PRESENTATION: A 78-year-old Italian woman was admitted to our emergency department because she noticed blurry vision in both eyes. She did not report fever, fatigue, or neurological symptoms in the last few days. Multimodal imaging showed the presence of bilateral hyperfluorescent lesions with a linear distribution, that corresponded to hypocyanescent spots on indocyanine green angiography. Antibody serology showed the presence of IgM antibodies, IgG antibodies, and ribonucleic acid (RNA) for WNV. Magnetic resonance imaging (MRI) of the brain ruled out central nervous system involvement. Three months later, the patient reported spontaneous resolution of her symptoms and remission of the chorioretinal infiltrates. CONCLUSIONS: In endemic areas, it is important to think of acute WNV infection as an explanatory etiology in cases of multifocal chorioretinitis, even without neurological involvement.
Assuntos
Coriorretinite , Infecções Oculares Virais , Febre do Nilo Ocidental , Vírus do Nilo Ocidental , Humanos , Feminino , Idoso , Febre do Nilo Ocidental/complicações , Febre do Nilo Ocidental/diagnóstico , Febre do Nilo Ocidental/epidemiologia , Infecções Oculares Virais/diagnóstico , Coriorretinite/etiologia , Corpo Vítreo/patologia , Anticorpos AntiviraisAssuntos
Adenocarcinoma/tratamento farmacológico , Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico , Receptores ErbB/metabolismo , Neoplasias Pulmonares/tratamento farmacológico , Piperazinas/uso terapêutico , Inibidores de Proteínas Quinases/uso terapêutico , Acrilamidas , Adenocarcinoma/patologia , Adenocarcinoma de Pulmão , Compostos de Anilina , Carcinoma Pulmonar de Células não Pequenas/patologia , Feminino , Humanos , Neoplasias Pulmonares/patologia , Pessoa de Meia-Idade , Metástase Neoplásica , Piperazinas/farmacologia , Inibidores de Proteínas Quinases/farmacologiaAssuntos
Suplementos Nutricionais/efeitos adversos , Oftalmopatias/induzido quimicamente , Fitoterapia/efeitos adversos , Angiofluoresceinografia , Humanos , Edema Macular/induzido quimicamente , Edema Macular/diagnóstico , Niacina/efeitos adversos , Preparações de Plantas/efeitos adversos , Vasos Retinianos/patologiaRESUMO
PURPOSE: To report the capability of autofluorescence as a novel approach to diagnosing macular holes. DESIGN: Observational case report. METHODS: In an institutional study, autofluorescence photos and optical coherence tomography scans of two patients who had surgery for macular holes were reviewed. RESULTS: Macular hole cases had a strong subfoveal autofluorescence signal, which disappeared after surgical closure of the macular hole. CONCLUSIONS: Autofluorescence is a novel approach to demonstrating a macular hole. This technique can also be used to confirm postoperative outcome after macular hole repair. A lack of autofluorescence corresponds to macular hole closure.
